Blog about Diabetes People Problems

It is caused by a buildup of lactic acid in the blood. Lactic acidosis is a medical emergency that must be treated in a hospital. Notify your doctor immediately if you experience any of the following: Symptoms of lactic acidosis may include: Dizziness, sleepiness, low body temperature, extreme weakness or tiredness, rapid breathing or trouble breathing, light-headedness, slow or irregular heartbeat, unexpected or unusual stomach discomfort, unusual muscle pain Glucophage (Metformin) could cause a very rare–but potentially fatal–side effect known as lactic acidosis. Glucophage (Metformin) could cause a very rare–but potentially fatal–side effect known as lactic acidosis. Notify your doctor immediately if you experience any of the following: Symptoms of lactic acidosis may include: Dizziness, low body temperature, unexpected or unusual stomach discomfort, rapid breathing or trouble breathing, sleepiness, light-headedness, slow or irregular heartbeat, extreme weakness or tiredness, unusual muscle pain . The problem is most likely to occur in people whose liver or kidneys are not working well, and in those who have multiple medical problems, take several medications, or have congestive heart failure. The risk also is higher if you are an older adult or drink alcohol. Be sure the doctor knows ahead of time that you are using this medication. If you have any questions about Metformin , pharmacist, please talk with your doctor, or other health care provider. Type 2 (non-insulin dependent) diabetes , when diet alone has failed to fully control blood sugar. Treatment is combined with a balanced diet and exercise. Some people have developed a life-threatening condition called lactic acidosis while taking metformin. Before taking metformin, tell your doctor if you have liver disease or a history of heart disease. It does not contain all information about Metformin (Glucophage) . It also helps to make your body more sensitive to the insulin that you naturally produce. It works by decreasing the amount of sugar that the liver produces and the intestines absorb. Do not use metformin if you have kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Type 2 diabetes mellitus is characterized differently due to insulin resistance or reduced insulin sensitivity, combined with reduced insulin secretion. The defective responsiveness of body tissues to insulin almost certainly involves the insulin receptor in cell membranes. In the early stage the predominant abnormality is reduced insulin sensitivity, characterized by elevated levels of insulin in the blood. At this stage hyperglycemia can be reversed by a variety of measures and medications that improve insulin sensitivity or reduce glucose production by the liver. As the disease progresses the impairment of insulin secretion worsens, and therapeutic replacement of insulin often becomes necessary.
There are numerous theories as to the exact cause and mechanism in type 2 diabetes. Central obesity (fat concentrated around the waist in relation to abdominal organs, but not subcutaneous fat) is known to predispose individuals for insulin resistance. Abdominal fat is especially active hormonally, secreting a group of hormones called adipokines that may possibly impair glucose tolerance. Obesity is found in approximately 55% of patients diagnosed with type 2 diabetes.[10] Other factors include aging (about 20% of elderly patients in North America have diabetes) and family history (type 2 is much more common in those with close relatives who have had it). In the last decade, type 2 diabetes has increasingly begun to affect children and adolescents, likely in connection with the increased prevalence of childhood obesity seen in recent decades in some places.

Type 1 diabetes mellitus is characterized by loss of the insulin-producing beta cells of the islets of Langerhans in the pancreas, leading to a deficiency of insulin. The main cause of this beta cell loss is a T-cell mediated autoimmune attack. There is no known preventative measure that can be taken against type 1 diabetes, which comprises up to 10% of diabetes mellitus cases in North America and Europe (though this varies by geographical location). Most affected people are otherwise healthy and of a healthy weight when onset occurs. Sensitivity and responsiveness to insulin are usually normal, especially in the early stages. Type 1 diabetes can affect children or adults but was traditionally termed “juvenile diabetes” because it represents a majority of cases of diabetes affecting children.